Antonelli M, Pennisi MA, Pelosi P, Gregoretti C, Squadrone V, Rocco M, Cecchini L, Chiumello D, Severgnini P, Proietti R, Navalesi P, Conti G. Anesthesiology. 2004 Jan;100(1):16-24
Study of 33 patients with COPD treated with helmet NPPV, compared with 33 historical controls treated with face mask NPPV. In the helmet group, no patients were unable to tolerate NPPV, whereas five of the control group required intubation. Authors conclude that helmet NPPV 'can be used to treat chronic COPD with acute exacerbation'.
Link to abstract.
Principi T, Pantanetti S, Catani F, Elisei D, Gabbanelli V, Pelaia P, Leoni P. Intensive Care Med. 2004 Jan;30(1):147-50
Comparison study of nCPAP through helmet vs face mask on 17 patients with moderate to severe acute respiratory failure. Arterial oxygen saturation, heart rate, respiratory rate and blood pressure were measured. Authors conclude early nCPAP with helmet imrpoves oxygentation in this scenario.
Link to abstract.