Cammarota G, Longhini F, Perucca R, Ronco C, Colombo D, Messina A, Vaschetto R, Navalesi P.
Anesthesiology. 2016 Dec;125(6):1181-1189
Randomised trial of 15 patients undergoing three 30-minutes ventilation trials using two different helmets. The ventiltion modes were randomly applied: pneumatically triggered pressure support ventilation (PSP), neurally adjusted ventilatory assist (NAVA) and neurally controlled pressure support (PSN). The latter is a new proposed setting of the NAVA mode. Authors conclude that PSN improves comfort and patient-ventilator interactions in this scenario.
Link to abstract.
Olivieri C, Longhini F, Cena T, Cammarota G, Vaschetto R, Messina A, Berni P, Magnani C, Della Corte F, Navalesi P. Anesthesiology. 2016 Jan;124(1):101-8
This study set out to assess the efficacy and safety of the new helmet (NH) in comparison to the standard helmet (SH) for the prevention of post-extubation respiratory failure (PERF). Both devices were also compared with the endotracheal tube (ETT) in place before extubation. Each of the 14 patients underwent three 30 minutes trials in pressure support ventilation, starting with ETT and after extubation, with a SH (Castar R, Intersurgical) and NH in a random order. Several parameters were evaluated including comfort, triggering delays, rates of pressurization, respiratory drive and frequency, arterial blood gases (ABGs) and rate of asynchrony. Findings have shown that the use of NH improved comfort, inspiratory trigger delay, pressurization and patient’s inspiratory time. On the other hand, respiratory drive and frequency, ABGs and rate of asynchrony were comparable between the two devices. Moreover, ETT outperformed both devices in all the parameters, apart from respiratory rate and asynchronies. Therefore, the NH provided a superior comfort and better patient-ventilator interaction in comparison to the SH.
Link to abstract.
Antonelli M, Pennisi MA, Pelosi P, Gregoretti C, Squadrone V, Rocco M, Cecchini L, Chiumello D, Severgnini P, Proietti R, Navalesi P, Conti G. Anesthesiology. 2004 Jan;100(1):16-24
Study of 33 patients with COPD treated with helmet NPPV, compared with 33 historical controls treated with face mask NPPV. In the helmet group, no patients were unable to tolerate NPPV, whereas five of the control group required intubation. Authors conclude that helmet NPPV 'can be used to treat chronic COPD with acute exacerbation'.
Link to abstract.