Squadrone V, Massaia M, Bruno B, Marmont F, Falda M, Bagna C, Bertone S, Filippini C, Slutsky AS, Vitolo U, Boccadoro M, Ranieri VM. Intensive Care Med. 2010 Oct; 36(10):1666-74
Study to determine effectiveness of early CPAP delivered in the ward to prevent occurrence of ALI requiring intensive care admission for mechanical ventilation. Primary outcomes measured were need of mechanical ventilation and intubation rate among patients requiring ICU admission. Authors conclude early CPAP in this scenario prevents 'evolution to acute lung injury'.
Link to abstract.